p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming

Human induced pluripotent stem (iPS) cells have great potential in regenerative medicine, but this depends on the integrity of their genomes. iPS cells have been found to contain a large number of de novo genetic alterations due to DNA damage response during reprogramming. Thus, to maintain the gene...

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Detalles Bibliográficos
Autores principales: Gong, Lu, Pan, Xiao, Chen, Haide, Rao, Lingjun, Zeng, Yelin, Hang, Honghui, Peng, Jinrong, Xiao, Lei, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118801/
https://www.ncbi.nlm.nih.gov/pubmed/27874035
http://dx.doi.org/10.1038/srep37281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118801/
https://www.ncbi.nlm.nih.gov/pubmed/27874035
http://dx.doi.org/10.1038/srep37281

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