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Harnessing short poly(A)-binding protein-interacting peptides for the suppression of nonsense-mediated mRNA decay
Nonsense-mediated mRNA decay (NMD) is a cellular process that eliminates messenger RNA (mRNA) substrates with premature translation termination codons (PTCs). In addition, NMD regulates the expression of a number of physiological mRNAs, for example transcripts containing long 3′ UTRs. Current models...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118804/ https://www.ncbi.nlm.nih.gov/pubmed/27874031 http://dx.doi.org/10.1038/srep37311 |