An anti-TNF-α antibody mimetic to treat ocular inflammation

Infliximab is an antibody that neutralizes TNF-α and is used principally by systemic administration to treat many inflammatory disorders. We prepared the antibody mimetic Fab-PEG-Fab (FpF(infliximab)) for direct intravitreal injection to assess whether such formulations have biological activity and...

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Detalles Bibliográficos
Autores principales: Khalili, Hanieh, Lee, Richard W., Khaw, Peng T., Brocchini, Steve, Dick, Andrew D., Copland, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118814/
https://www.ncbi.nlm.nih.gov/pubmed/27874029
http://dx.doi.org/10.1038/srep36905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118814/
https://www.ncbi.nlm.nih.gov/pubmed/27874029
http://dx.doi.org/10.1038/srep36905

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