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The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling

Members of the Erm methyltransferase family modify 23S rRNA of the bacterial ribosome and render cross-resistance to macrolides and multiple distantly related antibiotics. Previous studies have shown that the expression of erm is activated when a macrolide-bound ribosome stalls the translation of th...

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Detalles Bibliográficos
Autores principales: Dzyubak, Ekaterina, Yap, Mee-Ngan F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118997/
https://www.ncbi.nlm.nih.gov/pubmed/27645242
http://dx.doi.org/10.1128/AAC.01806-16