Cargando…

The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation

Metabolic stress induces autophagy as an alternative source of energy and metabolites. Insufficient autophagy in nutrient-deprived cancer cells would be beneficial for cancer therapy. Here, we performed a functional screen in search of novel autophagy regulators from natural products. We showed that...

Descripción completa

Detalles Bibliográficos
Autores principales: Lao, Yuanzhi, Wan, Gang, Liu, Zhenyan, Wang, Xiaoyu, Ruan, Ping, Xu, Wei, Xu, Danqing, Xie, Weidong, Zhang, Yaou, Xu, Hongxi, Xu, Naihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119057/
https://www.ncbi.nlm.nih.gov/pubmed/24642486
http://dx.doi.org/10.4161/auto.28034