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The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation
Metabolic stress induces autophagy as an alternative source of energy and metabolites. Insufficient autophagy in nutrient-deprived cancer cells would be beneficial for cancer therapy. Here, we performed a functional screen in search of novel autophagy regulators from natural products. We showed that...
Autores principales: | Lao, Yuanzhi, Wan, Gang, Liu, Zhenyan, Wang, Xiaoyu, Ruan, Ping, Xu, Wei, Xu, Danqing, Xie, Weidong, Zhang, Yaou, Xu, Hongxi, Xu, Naihan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119057/ https://www.ncbi.nlm.nih.gov/pubmed/24642486 http://dx.doi.org/10.4161/auto.28034 |
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