Hyperoxia downregulates angiotensin-converting enzyme-2 in human fetal lung fibroblasts

BACKGROUND: Angiotensin (ANG) II is involved in experimental hyperoxia-induced lung fibrosis. Angiotensin-converting enzyme-2 (ACE-2) degrades ANG II and is thus protective, but is downregulated in adult human and experimental lung fibrosis. Hyperoxia is a known cause of chronic fibrotic lung diseas...

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Detalles Bibliográficos
Autores principales: Oarhe, Chinyere I., Dang, Vinh, Dang, MyTrang, Nguyen, Hang, Gopallawa, Indiwari, Gewolb, Ira H., Uhal, Bruce D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119454/
https://www.ncbi.nlm.nih.gov/pubmed/25665060
http://dx.doi.org/10.1038/pr.2015.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119454/
https://www.ncbi.nlm.nih.gov/pubmed/25665060
http://dx.doi.org/10.1038/pr.2015.27

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