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Hyperoxia downregulates angiotensin-converting enzyme-2 in human fetal lung fibroblasts

BACKGROUND: Angiotensin (ANG) II is involved in experimental hyperoxia-induced lung fibrosis. Angiotensin-converting enzyme-2 (ACE-2) degrades ANG II and is thus protective, but is downregulated in adult human and experimental lung fibrosis. Hyperoxia is a known cause of chronic fibrotic lung diseas...

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Detalles Bibliográficos
Autores principales:	Oarhe, Chinyere I., Dang, Vinh, Dang, MyTrang, Nguyen, Hang, Gopallawa, Indiwari, Gewolb, Ira H., Uhal, Bruce D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119454/ https://www.ncbi.nlm.nih.gov/pubmed/25665060 http://dx.doi.org/10.1038/pr.2015.27

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