Parallel reverse genetic screening in mutant human cells using transcriptomics

Reverse genetic screens have driven gene annotation and target discovery in model organisms. However, many disease‐relevant genotypes and phenotypes cannot be studied in lower organisms. It is therefore essential to overcome technical hurdles associated with large‐scale reverse genetics in human cel...

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Detalles Bibliográficos
Autores principales: Gapp, Bianca V, Konopka, Tomasz, Penz, Thomas, Dalal, Vineet, Bürckstümmer, Tilmann, Bock, Christoph, Nijman, Sebastian MB
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119491/
https://www.ncbi.nlm.nih.gov/pubmed/27482057
http://dx.doi.org/10.15252/msb.20166890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119491/
https://www.ncbi.nlm.nih.gov/pubmed/27482057
http://dx.doi.org/10.15252/msb.20166890

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