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Optimisation and validation of a PCR for antigen receptor rearrangement (PARR) assay to detect clonality in canine lymphoid malignancies

PCR for antigen receptor gene rearrangements (PARR) analysis is being increasingly used to assist diagnosis of canine lymphoma. In this study, PARR was carried out on consecutive samples received as part of routine diagnostic practice from 271 patients: 195 with lymphoid malignancies, 53 with reacti...

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Detalles Bibliográficos
Autores principales: Waugh, Elspeth M., Gallagher, Alice, Haining, Hayley, Johnston, Pamela E.J., Marchesi, Francesco, Jarrett, Ruth F., Morris, Joanna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119497/
https://www.ncbi.nlm.nih.gov/pubmed/27863542
http://dx.doi.org/10.1016/j.vetimm.2016.10.008