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Effects of ligand binding on the stability of aldo–keto reductases: Implications for stabilizer or destabilizer chaperones
Ligands such as enzyme inhibitors stabilize the native conformation of a protein upon binding to the native state, but some compounds destabilize the native conformation upon binding to the non‐native state. The former ligands are termed “stabilizer chaperones” and the latter ones “destabilizer chap...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119574/ https://www.ncbi.nlm.nih.gov/pubmed/27595938 http://dx.doi.org/10.1002/pro.3036 |