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HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways

Sensory neuropathies are the most common neurological complication of HIV. Of these, distal sensory polyneuropathy (DSP) is directly caused by HIV infection and characterized by length-dependent axonal degeneration of dorsal root ganglion (DRG) neurons. Mechanisms for axonal degeneration in DSP rema...

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Detalles Bibliográficos
Autores principales: Berth, Sarah H., Mesnard-Hoaglin, Nichole, Wang, Bin, Kim, Hajwa, Song, Yuyu, Sapar, Maria, Morfini, Gerardo, Brady, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119683/
https://www.ncbi.nlm.nih.gov/pubmed/27872270
http://dx.doi.org/10.1177/1759091416679073