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Extensive Association of Common Disease Variants with Regulatory Sequence

Overlap between non-coding DNA regulatory sequences and common variant associations can help to identify specific cell and tissue types that are relevant for particular diseases. In a systematic manner, we analyzed variants from 94 genome-wide association studies (reporting at least 12 loci at p<...

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Detalles Bibliográficos
Autores principales: Mokry, Michal, Harakalova, Magdalena, Asselbergs, Folkert W., de Bakker, Paul I. W., Nieuwenhuis, Edward E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119736/
https://www.ncbi.nlm.nih.gov/pubmed/27875544
http://dx.doi.org/10.1371/journal.pone.0165893