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An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition

Chromatin immunoprecipitation and DNA sequencing (ChIP-seq) has been instrumental in inferring the roles of histone post-translational modifications in the regulation of transcription, chromatin compaction and other cellular processes that require modulation of chromatin structure. However, analysis...

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Detalles Bibliográficos
Autores principales: Egan, Brian, Yuan, Chih-Chi, Craske, Madeleine Lisa, Labhart, Paul, Guler, Gulfem D., Arnott, David, Maile, Tobias M., Busby, Jennifer, Henry, Chisato, Kelly, Theresa K., Tindell, Charles A., Jhunjhunwala, Suchit, Zhao, Feng, Hatton, Charlie, Bryant, Barbara M., Classon, Marie, Trojer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119738/
https://www.ncbi.nlm.nih.gov/pubmed/27875550
http://dx.doi.org/10.1371/journal.pone.0166438