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The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways

The β-nitrostyrene family have been implicated for anti-cancer property. However, the pharmacological role of β-nitrostyrene in esophageal cancer remain unclear. Here, a β-nitrostyrene derivative, CYT-Rx20, was synthesized and assessed for its anti-cancer activities and underlying mechanism in esoph...

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Detalles Bibliográficos
Autores principales: Chiu, Wen-Chin, Lee, Yi-Chen, Su, Yu-Han, Wang, Yen-Yun, Tsai, Chun-Hao, Hou, Yi-An, Wang, Chie-Hong, Huang, Ying-Fong, Huang, Chih-Jen, Chou, Shah-Hwa, Hsieh, Pei-Wen, Yuan, Shyng-Shiou F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119777/
https://www.ncbi.nlm.nih.gov/pubmed/27875549
http://dx.doi.org/10.1371/journal.pone.0166453