Cargando…
The Synthetic β-Nitrostyrene Derivative CYT-Rx20 Inhibits Esophageal Tumor Growth and Metastasis via PI3K/AKT and STAT3 Pathways
The β-nitrostyrene family have been implicated for anti-cancer property. However, the pharmacological role of β-nitrostyrene in esophageal cancer remain unclear. Here, a β-nitrostyrene derivative, CYT-Rx20, was synthesized and assessed for its anti-cancer activities and underlying mechanism in esoph...
Autores principales: | Chiu, Wen-Chin, Lee, Yi-Chen, Su, Yu-Han, Wang, Yen-Yun, Tsai, Chun-Hao, Hou, Yi-An, Wang, Chie-Hong, Huang, Ying-Fong, Huang, Chih-Jen, Chou, Shah-Hwa, Hsieh, Pei-Wen, Yuan, Shyng-Shiou F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119777/ https://www.ncbi.nlm.nih.gov/pubmed/27875549 http://dx.doi.org/10.1371/journal.pone.0166453 |
Ejemplares similares
-
3’-hydroxy-4’-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction
por: Tsai, Chun-Hao, et al.
Publicado: (2017) -
Organocatalytic Michael Addition of 1,3-Dicarbonyl Indane Compounds to Nitrostyrenes
por: Jiang, Zhen-Yu, et al.
Publicado: (2010) -
Denitrative Cross-Couplings of Nitrostyrenes
por: Marčeková, Michaela, et al.
Publicado: (2020) -
Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyrene
por: Messerschmitt, Patrick J., et al.
Publicado: (2012) -
β-Nitrostyrenes as Potential Anti-leishmanial Agents
por: Shafi, Syed, et al.
Publicado: (2016)