Inhibition of Notch Signaling Attenuates Schistosomiasis Hepatic Fibrosis via Blocking Macrophage M2 Polarization

Macrophages play a key role in the pathogenesis of liver granuloma and fibrosis in schistosomiasis. However, the underlying mechanisms have not been fully characterized. This study revealed that the macrophages infiltrating the liver tissues in a murine model of Schistosoma japonica infection exhibi...

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Detalles Bibliográficos
Autores principales: Zheng, Shaoping, Zhang, Peige, Chen, Yixiong, Zheng, Shaojiang, Zheng, Liping, Weng, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119780/
https://www.ncbi.nlm.nih.gov/pubmed/27875565
http://dx.doi.org/10.1371/journal.pone.0166808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119780/
https://www.ncbi.nlm.nih.gov/pubmed/27875565
http://dx.doi.org/10.1371/journal.pone.0166808

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