Chidamide Inhibits Aerobic Metabolism to Induce Pancreatic Cancer Cell Growth Arrest by Promoting Mcl-1 Degradation

Pancreatic cancer is a fatal malignancy worldwide and urgently requires valid therapies. Previous research showed that the HDAC inhibitor chidamide is a promising anti-cancer agent in pancreatic cancer cell lines. In this study, we elucidate a probable underlying anti-cancer mechanism of chidamide i...

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Detalles Bibliográficos
Autores principales: He, Mu, Qiao, Zhixin, Wang, Yanbing, Kuai, Qiyuan, Li, Changlan, Wang, Yu, Jiang, Xingwei, Wang, Xuanlin, Li, Weijing, He, Min, Ren, Suping, Yu, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119787/
https://www.ncbi.nlm.nih.gov/pubmed/27875574
http://dx.doi.org/10.1371/journal.pone.0166896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119787/
https://www.ncbi.nlm.nih.gov/pubmed/27875574
http://dx.doi.org/10.1371/journal.pone.0166896

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