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Changes in Intracellular Na(+) following Enhancement of Late Na(+) Current in Virtual Human Ventricular Myocytes

The slowly inactivating or late Na(+) current, I(Na-L), can contribute to the initiation of both atrial and ventricular rhythm disturbances in the human heart. However, the cellular and molecular mechanisms that underlie these pro-arrhythmic influences are not fully understood. At present, the major...

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Detalles Bibliográficos
Autores principales: Cardona, Karen, Trenor, Beatriz, Giles, Wayne R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119830/
https://www.ncbi.nlm.nih.gov/pubmed/27875582
http://dx.doi.org/10.1371/journal.pone.0167060