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Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels
The activity of serotonin (5-HT) neurons is critical for mood regulation. In a mouse model of chronic social isolation, a known risk factor for depressive illness, we show that 5-HT neurons in the dorsal raphe nucleus are less responsive to stimulation. Probing the responsible cellular mechanisms pi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119885/ https://www.ncbi.nlm.nih.gov/pubmed/27874831 http://dx.doi.org/10.7554/eLife.21416 |