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Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

The activity of serotonin (5-HT) neurons is critical for mood regulation. In a mouse model of chronic social isolation, a known risk factor for depressive illness, we show that 5-HT neurons in the dorsal raphe nucleus are less responsive to stimulation. Probing the responsible cellular mechanisms pi...

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Detalles Bibliográficos
Autores principales:	Sargin, Derya, Oliver, David K, Lambe, Evelyn K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119885/ https://www.ncbi.nlm.nih.gov/pubmed/27874831 http://dx.doi.org/10.7554/eLife.21416

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