The endosomal transcriptional regulator RNF11 integrates degradation and transport of EGFR

Stimulation of cells with epidermal growth factor (EGF) induces internalization and partial degradation of the EGF receptor (EGFR) by the endo-lysosomal pathway. For continuous cell functioning, EGFR plasma membrane levels are maintained by transporting newly synthesized EGFRs to the cell surface. T...

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Detalles Bibliográficos
Autores principales: Scharaw, Sandra, Iskar, Murat, Ori, Alessandro, Boncompain, Gaelle, Laketa, Vibor, Poser, Ina, Lundberg, Emma, Perez, Franck, Beck, Martin, Bork, Peer, Pepperkok, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119934/
https://www.ncbi.nlm.nih.gov/pubmed/27872256
http://dx.doi.org/10.1083/jcb.201601090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119934/
https://www.ncbi.nlm.nih.gov/pubmed/27872256
http://dx.doi.org/10.1083/jcb.201601090

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