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Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid

With their essential role in inner ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by cross-linkers of the plastin, fascin, and espin families. Although mice lacking espin (ESPN) have no vestibular or...

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Detalles Bibliográficos
Autores principales: Krey, Jocelyn F., Krystofiak, Evan S., Dumont, Rachel A., Vijayakumar, Sarath, Choi, Dongseok, Rivero, Francisco, Kachar, Bechara, Jones, Sherri M., Barr-Gillespie, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119939/
https://www.ncbi.nlm.nih.gov/pubmed/27811163
http://dx.doi.org/10.1083/jcb.201606036