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GTPase cross talk regulates TRAPPII activation of Rab11 homologues during vesicle biogenesis

Rab guanosine triphosphatases (GTPases) control cellular trafficking pathways by regulating vesicle formation, transport, and tethering. Rab11 and its paralogs regulate multiple secretory and endocytic recycling pathways, yet the guanine nucleotide exchange factor (GEF) that activates Rab11 in most...

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Detalles Bibliográficos
Autores principales: Thomas, Laura L., Fromme, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119942/
https://www.ncbi.nlm.nih.gov/pubmed/27872253
http://dx.doi.org/10.1083/jcb.201608123