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Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective

Mechanical strain due to increased pressure or swelling activates inflammatory responses in many neural systems. As cytokines and chemokine messengers lead to both pro-inflammatory and neuroprotective actions, understanding the signaling patterns triggered by mechanical stress may help improve overa...

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Detalles Bibliográficos
Autores principales: Lim, Jason C., Lu, Wennan, Beckel, Jonathan M., Mitchell, Claire H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120082/
https://www.ncbi.nlm.nih.gov/pubmed/27932954
http://dx.doi.org/10.3389/fncel.2016.00270