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NEMO-Binding Domain Peptide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting the NF-κB Signaling Pathway

The aim of the present study is to investigate the protective effects and relevant mechanisms exerted by NEMO-binding domain peptide (NBD) against lipopolysaccharide- (LPS-) induced acute lung injury (ALI) in mice. The ALI model was induced by intratracheally administered atomized LPS (5 mg/kg) to B...

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Detalles Bibliográficos
Autores principales: Huang, Jianhua, Li, Li, Yuan, Weifeng, Zheng, Linxin, Guo, Zhenhui, Huang, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120201/
https://www.ncbi.nlm.nih.gov/pubmed/27956761
http://dx.doi.org/10.1155/2016/7349603