TWIST1 drives cisplatin resistance and cell survival in an ovarian cancer model, via upregulation of GAS6, L1CAM, and Akt signalling

Epithelial ovarian cancer (EOC) is the most deadly gynaecologic malignancy due to late onset of symptoms and propensity towards drug resistance. Epithelial-mesenchymal transition (EMT) has been linked to the development of chemoresistance in other cancers, yet little is known regarding its role in E...

Descripción completa

Detalles Bibliográficos
Autores principales: Roberts, Cai M., Tran, Michelle A., Pitruzzello, Mary C., Wen, Wei, Loeza, Joana, Dellinger, Thanh H., Mor, Gil, Glackin, Carlotta A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120297/
https://www.ncbi.nlm.nih.gov/pubmed/27876874
http://dx.doi.org/10.1038/srep37652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120297/
https://www.ncbi.nlm.nih.gov/pubmed/27876874
http://dx.doi.org/10.1038/srep37652

Ejemplares similares