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Common variants in the PARL and PINK1 genes increase the risk to leprosy in Han Chinese from South China

Leprosy is a chronic infectious and neurological disease caused by Mycobacterium leprae, an unculturable pathogen with massive genomic decay and dependence on host metabolism. We hypothesized that mitochondrial genes PARL and PINK1 would confer risk to leprosy. Thirteen tag SNPs of PARL and PINK1 we...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Zhang, Deng-Feng, Feng, Jia-Qi, Li, Guo-Dong, Li, Xiao-An, Yu, Xiu-Feng, Long, Heng, Li, Yu-Ye, Yao, Yong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120299/
https://www.ncbi.nlm.nih.gov/pubmed/27876828
http://dx.doi.org/10.1038/srep37086