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Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition

Although increases in cardiovascular load (pressure overload) are known to elicit ventricular remodeling including cardiomyocyte hypertrophy and interstitial fibrosis, the molecular mechanisms of pressure overload or AngII -induced cardiac interstitial fibrosis remain elusive. In this study, serpinE...

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Detalles Bibliográficos
Autores principales: Li, Xuelian, Zhao, Dandan, Guo, Zhenfeng, Li, Tianshi, Qili, Muge, Xu, Bozhi, Qian, Ming, Liang, Haihai, E, Xiaoqiang, Chege Gitau, Samuel, Wang, Lu, Huangfu, Longtao, Wu, Qiuxia, Xu, Chaoqian, Shan, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120308/
https://www.ncbi.nlm.nih.gov/pubmed/27876880
http://dx.doi.org/10.1038/srep37635