Reconstitution of Targeted Deadenylation by the Ccr4-Not Complex and the YTH Domain Protein Mmi1

Ccr4-Not is a conserved protein complex that shortens the 3′ poly(A) tails of eukaryotic mRNAs to regulate transcript stability and translation into proteins. RNA-binding proteins are thought to facilitate recruitment of Ccr4-Not to certain mRNAs, but lack of an in-vitro-reconstituted system has slo...

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Detalles Bibliográficos
Autores principales: Stowell, James A.W., Webster, Michael W., Kögel, Alexander, Wolf, Jana, Shelley, Kathryn L., Passmore, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120349/
https://www.ncbi.nlm.nih.gov/pubmed/27851962
http://dx.doi.org/10.1016/j.celrep.2016.10.066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120349/
https://www.ncbi.nlm.nih.gov/pubmed/27851962
http://dx.doi.org/10.1016/j.celrep.2016.10.066

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