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Downregulation of long non-coding RNA H19 promotes P19CL6 cells proliferation and inhibits apoptosis during late-stage cardiac differentiation via miR-19b-modulated Sox6

BACKGROUND: Regulating cardiac differentiation to maintain normal heart development and function is very important. At present, biological functions of H19 in cardiac differentiation is not completely clear. METHODS: To explore the functional effect of H19 during cardiac differentiation. Expression...

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Detalles Bibliográficos
Autores principales: Han, Yu, Xu, Hongdang, Cheng, Jiangtao, Zhang, Yanwei, Gao, Chuanyu, Fan, Taibing, Peng, Bangtian, Li, Bin, Liu, Lin, Cheng, Zhaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120414/
https://www.ncbi.nlm.nih.gov/pubmed/27895893
http://dx.doi.org/10.1186/s13578-016-0123-5