Nuclear envelope structural defect underlies the main cause of aneuploidy in ovarian carcinogenesis

BACKGROUND: The Cancer Atlas project has shown that p53 is the only commonly (96 %) mutated gene found in high-grade serous epithelial ovarian cancer, the major histological subtype. Another general genetic change is extensive aneuploidy caused by chromosomal numerical instability, which is thought...

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Detalles Bibliográficos
Autores principales: Capo-chichi, Callinice D., Yeasky, Toni M., Smith, Elizabeth R., Xu, Xiang-Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120486/
https://www.ncbi.nlm.nih.gov/pubmed/27875985
http://dx.doi.org/10.1186/s12860-016-0114-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120486/
https://www.ncbi.nlm.nih.gov/pubmed/27875985
http://dx.doi.org/10.1186/s12860-016-0114-8

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