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Melatonin improves non-alcoholic fatty liver disease via MAPK-JNK/P38 signaling in high-fat-diet-induced obese mice

BACKGROUND: Melatonin can regulate lipid metabolism, increase insulin sensitivity, regulate glucose metabolism and reduce body weight. This study is aimed to determine the effects and mechanism of action of melatonin on non-alcoholic fatty liver disease (NAFLD) in high-fat-diet (HFD) induced obese m...

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Detalles Bibliográficos
Autores principales: Sun, Hang, Wang, Xingchun, Chen, Jiaqi, Song, Kexiu, Gusdon, Aaron M., Li, Liang, Bu, Le, Qu, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120511/
https://www.ncbi.nlm.nih.gov/pubmed/27876064
http://dx.doi.org/10.1186/s12944-016-0370-9