SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis

Although cancers are considered stem cell diseases, mechanisms involving stem cell alterations are poorly understood. Squamous cell carcinoma (SQCC) is the second most common lung cancer, and its pathogenesis appears to hinge on changes in the stem cell behavior of basal cells in the bronchial airwa...

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Detalles Bibliográficos
Autores principales: Kim, Bo Ram, Van de Laar, Emily, Cabanero, Michael, Tarumi, Shintaro, Hasenoeder, Stefan, Wang, Dennis, Virtanen, Carl, Suzuki, Takaya, Bandarchi, Bizhan, Sakashita, Shingo, Pham, Nhu An, Lee, Sharon, Keshavjee, Shaf, Waddell, Thomas K., Tsao, Ming-Sound, Moghal, Nadeem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120804/
https://www.ncbi.nlm.nih.gov/pubmed/27880766
http://dx.doi.org/10.1371/journal.pbio.1002581

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120804/
https://www.ncbi.nlm.nih.gov/pubmed/27880766
http://dx.doi.org/10.1371/journal.pbio.1002581

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