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Human Genome-Wide RNAi Screen for Host Factors That Facilitate Salmonella Invasion Reveals a Role for Potassium Secretion in Promoting Internalization

Salmonella enterica can actively invade the gastro-intestinal epithelium. This frequently leads to diarrheal disease, and also gives the pathogen access to phagocytes that can serve as vehicles for dissemination into deeper tissue. The ability to invade host cells is also important in maintaining th...

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Detalles Bibliográficos
Autores principales: Thornbrough, Joshua M., Gopinath, Adarsh, Hundley, Tom, Worley, Micah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120809/
https://www.ncbi.nlm.nih.gov/pubmed/27880807
http://dx.doi.org/10.1371/journal.pone.0166916