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AMPA Receptor Antagonist NBQX Decreased Seizures by Normalization of Perineuronal Nets

Epilepsy is a serious brain disorder with diverse seizure types and epileptic syndromes. AMPA receptor antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzoquinoxaline-2,3-dione (NBQX) attenuates spontaneous recurrent seizures in rats. However, the anti-epileptic effect of NBQX in chronic epilepsy mode...

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Detalles Bibliográficos
Autores principales: Chen, Wen, Li, Yan-Shuang, Gao, Jing, Lin, Xiao-Ying, Li, Xiao-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120819/
https://www.ncbi.nlm.nih.gov/pubmed/27880801
http://dx.doi.org/10.1371/journal.pone.0166672