Effects of target-controlled infusion of high-dose naloxone on pain and hyperalgesia in a human thermal injury model: a study protocol: A randomized, double-blind, placebo-controlled, crossover trial with an enriched design

Mu-opioid-receptor antagonists have been extensively studied in experimental research as pharmacological tools uncovering mechanisms of pain modulation by the endogenous opioid system. In rodents, administration of high doses of mu-opioid-receptor antagonists after the resolution of an inflammatory...

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Detalles Bibliográficos
Autores principales: Springborg, Anders D., Jensen, Elisabeth K., Taylor, Bradley K., Werner, Mads U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
3300
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120919/
https://www.ncbi.nlm.nih.gov/pubmed/27861362
http://dx.doi.org/10.1097/MD.0000000000005336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120919/
https://www.ncbi.nlm.nih.gov/pubmed/27861362
http://dx.doi.org/10.1097/MD.0000000000005336

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