Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice

Cholestasis is a condition that leads to chronic hepatobiliary inflammation, fibrosis, and eventually cirrhosis. Many microRNAs (miRs) are known to play a role in fibrosis progression; however, the role of miR-21 during cholestasis remains unknown. Therefore, the aim of this study was to elucidate t...

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Detalles Bibliográficos
Autores principales: Kennedy, Lindsey, Meng, Fanyin, Venter, Julie, Zhou, Tianhao, Karstens, Walker, Hargrove, Laura, Wu, Nan, Kyritsi, Konstantina, Greene, John, Invernizzi, Pietro, Bernuzzi, Francesca, Glaser, Shannon, Francis, Heather, Alpini, Gianfranco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121007/
https://www.ncbi.nlm.nih.gov/pubmed/27775690
http://dx.doi.org/10.1038/labinvest.2016.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121007/
https://www.ncbi.nlm.nih.gov/pubmed/27775690
http://dx.doi.org/10.1038/labinvest.2016.112

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