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Activation of Carbonic Anhydrase IX by Alternatively Spliced Tissue Factor Under Late-Stage Tumor Conditions

Molecules of the coagulation pathway predispose patients to cancer-associated thrombosis and also trigger intracellular signaling pathways that promote cancer progression. The primary transcript of Tissue Factor, the main physiologic trigger of blood clotting, can undergo alternative splicing yieldi...

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Detalles Bibliográficos
Autores principales: Ramchandani, Divya, Unruh, Dusten, Lewis, Clayton S., Bogdanov, Vladimir Y., Weber, Georg F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121009/
https://www.ncbi.nlm.nih.gov/pubmed/27721473
http://dx.doi.org/10.1038/labinvest.2016.103