Transcription upregulation via force-induced direct stretching of chromatin

Mechanical forces play critical roles in the function of living cells. However, the underlying mechanisms of how forces influence nuclear events remain elusive. Here, we show that chromatin deformation as well as force-induced transcription of a green-fluorescent-protein (GFP) tagged bacterial-chrom...

Descripción completa

Detalles Bibliográficos
Autores principales: Tajik, Arash, Zhang, Yuejin, Wei, Fuxiang, Sun, Jian, Jia, Qiong, Zhou, Wenwen, Singh, Rishi, Khanna, Nimish, Belmont, Andrew S., Wang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121013/
https://www.ncbi.nlm.nih.gov/pubmed/27548707
http://dx.doi.org/10.1038/nmat4729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121013/
https://www.ncbi.nlm.nih.gov/pubmed/27548707
http://dx.doi.org/10.1038/nmat4729

Ejemplares similares