Cargando…

Actin polymerization‐dependent activation of Cas‐L promotes immunological synapse stability

The immunological synapse formed between a T‐cell and an antigen‐presenting cell is important for cell–cell communication during T‐cell‐mediated immune responses. Immunological synapse formation begins with stimulation of the T‐cell receptor (TCR). TCR microclusters are assembled and transported to...

Descripción completa

Detalles Bibliográficos
Autores principales: Santos, Luís C, Blair, David A, Kumari, Sudha, Cammer, Michael, Iskratsch, Thomas, Herbin, Olivier, Alexandropoulos, Konstantina, Dustin, Michael L, Sheetz, Michael P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121033/
https://www.ncbi.nlm.nih.gov/pubmed/27359298
http://dx.doi.org/10.1038/icb.2016.61