Insulin elevates leptin secretion and mRNA levels via cyclic AMP in 3T3-L1 adipocytes deprived of glucose

AIMS: Leptin plays an important role in the pathogenesis of obesity and diabetes, yet the regulatory mechanisms of this hormone have not been fully elucidated. In this study, we aimed to clarify the roles of insulin and glucose in leptin secretion and mRNA production using inhibitors of insulin sign...

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Detalles Bibliográficos
Autores principales: Tsubai, Tomomi, Noda, Yukihiro, Ito, Kazuma, Nakao, Makoto, Seino, Yusuke, Oiso, Yutaka, Hamada, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121139/
https://www.ncbi.nlm.nih.gov/pubmed/27896318
http://dx.doi.org/10.1016/j.heliyon.2016.e00194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121139/
https://www.ncbi.nlm.nih.gov/pubmed/27896318
http://dx.doi.org/10.1016/j.heliyon.2016.e00194

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