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Impact of CYP2C19 Variants on Clinical Efficacy of Clopidogrel and 1-Year Clinical Outcomes in Coronary Heart Patients Undergoing Percutaneous Coronary Intervention

The impact of pharmacogenetic variants of cytochrome P450 2C19 (CYP2C19) on clopidogrel-mediated effects on platelet inhibition, inflammatory response and endothelial function, as well as risk of major adverse cardiovascular events (MACE), in coronary heart patients undergoing percutaneous coronary...

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Detalles Bibliográficos
Autores principales: Sun, Hong, Qu, Qiang, Chen, Zhen-Fan, Tan, Sheng-Lan, Zhou, Hai-Jun, Qu, Jian, Chen, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121225/
https://www.ncbi.nlm.nih.gov/pubmed/27932982
http://dx.doi.org/10.3389/fphar.2016.00453