Screening of mutations affecting protein stability and dynamics of FGFR1—A simulation analysis

Single amino acid substitutions in Fibroblast Growth Factor Receptor 1 (FGFR1) destabilize protein and have been implicated in several genetic disorders like various forms of cancer, Kallamann syndrome, Pfeiffer syndrome, Jackson Weiss syndrome, etc. In order to gain functional insight into mutation...

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Detalles Bibliográficos
Autores principales: Doss, C. George Priya, Rajith, B., Garwasis, Nimisha, Mathew, Pretty Raju, Raju, Anand Solomon, Apoorva, K., William, Denise, Sadhana, N.R., Himani, Tanwar, Dike, IP.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121281/
https://www.ncbi.nlm.nih.gov/pubmed/27896051
http://dx.doi.org/10.1016/j.atg.2012.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121281/
https://www.ncbi.nlm.nih.gov/pubmed/27896051
http://dx.doi.org/10.1016/j.atg.2012.06.002

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