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Differential hexosamine biosynthetic pathway gene expression with type 2 diabetes
The hexosamine biosynthetic pathway (HBP) culminates in the attachment of O-linked β-N-acetylglucosamine (O-GlcNAc) onto serine/threonine residues of target proteins. The HBP is regulated by several modulators, i.e. O-linked β-N-acetylglucosaminyl transferase (OGT) and β-N-acetylglucosaminidase (OGA...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121314/ https://www.ncbi.nlm.nih.gov/pubmed/27896086 http://dx.doi.org/10.1016/j.ymgmr.2014.03.003 |