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Metyrapone, an inhibitor of cytochrome oxidases, does not affect viability in a neuroblastoma cell model of bilirubin toxicity

BACKGROUND: Unconjugated hyperbilirubinemia may cause brain damage in infants, and globally remains a source of neonatal morbidity and mortality. A significant inter-individual variability in vulnerability to bilirubin toxicity remains largely unexplained. An enzyme located in mitochondria oxidizes...

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Detalles Bibliográficos
Autores principales: Naguib Leerberg, Maria N., Alme, Tomas N., Hansen, Thor W.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121316/
https://www.ncbi.nlm.nih.gov/pubmed/27896088
http://dx.doi.org/10.1016/j.ymgmr.2014.04.002