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De-novo protein function prediction using DNA binding and RNA binding proteins as a test case
Of the currently identified protein sequences, 99.6% have never been observed in the laboratory as proteins and their molecular function has not been established experimentally. Predicting the function of such proteins relies mostly on annotated homologs. However, this has resulted in some erroneous...
Autores principales: | Peled, Sapir, Leiderman, Olga, Charar, Rotem, Efroni, Gilat, Shav-Tal, Yaron, Ofran, Yanay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121330/ https://www.ncbi.nlm.nih.gov/pubmed/27869118 http://dx.doi.org/10.1038/ncomms13424 |
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