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T-cell stimuli independently sum to regulate an inherited clonal division fate

In the presence of antigen and costimulation, T cells undergo a characteristic response of expansion, cessation and contraction. Previous studies have revealed that population-level reproducibility is a consequence of multiple clones exhibiting considerable disparity in burst size, highlighting the...

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Detalles Bibliográficos
Autores principales: Marchingo, J. M., Prevedello, G., Kan, A., Heinzel, S., Hodgkin, P. D., Duffy, K. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121331/
https://www.ncbi.nlm.nih.gov/pubmed/27869196
http://dx.doi.org/10.1038/ncomms13540