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The Hippo signalling pathway coordinates organ growth and limits developmental variability by controlling dilp8 expression

Coordination of organ growth during development is required to generate fit individuals with fixed proportions. We recently identified Drosophila Dilp8 as a key hormone in coupling organ growth with animal maturation. In addition, dilp8 mutant flies exhibit elevated fluctuating asymmetry (FA) demons...

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Detalles Bibliográficos
Autores principales: Boone, Emilie, Colombani, Julien, Andersen, Ditte S., Léopold, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121414/
https://www.ncbi.nlm.nih.gov/pubmed/27874005
http://dx.doi.org/10.1038/ncomms13505