Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

Viral subunit vaccines often contain immunodominant non-neutralizing epitopes that divert host immune responses. These epitopes should be eliminated in vaccine design, but there is no reliable method for evaluating an epitope's capacity to elicit neutralizing immune responses. Here we introduce...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Lanying, Tai, Wanbo, Yang, Yang, Zhao, Guangyu, Zhu, Qing, Sun, Shihui, Liu, Chang, Tao, Xinrong, Tseng, Chien-Te K., Perlman, Stanley, Jiang, Shibo, Zhou, Yusen, Li, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121417/
https://www.ncbi.nlm.nih.gov/pubmed/27874853
http://dx.doi.org/10.1038/ncomms13473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121417/
https://www.ncbi.nlm.nih.gov/pubmed/27874853
http://dx.doi.org/10.1038/ncomms13473

Ejemplares similares